A Rare Case of ETV6/MECOM Rearrangement in Therapy-Related Acute Myeloid Leukemia with t(3;12) and Monosomy 7

Clin Lab. 2017 Feb 1;63(2):415-418. doi: 10.7754/Clin.Lab.2016.160815.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Chromosome Deletion
  • Chromosomes, Human, Pair 12*
  • Chromosomes, Human, Pair 3*
  • Chromosomes, Human, Pair 7 / genetics
  • ETS Translocation Variant 6 Protein
  • Gene Fusion*
  • Gene Rearrangement*
  • Genetic Predisposition to Disease
  • Humans
  • Karyotyping
  • Leukemia, Myeloid, Acute / chemically induced
  • Leukemia, Myeloid, Acute / diagnosis
  • Leukemia, Myeloid, Acute / drug therapy
  • Leukemia, Myeloid, Acute / genetics*
  • MDS1 and EVI1 Complex Locus Protein / genetics*
  • Male
  • Middle Aged
  • Multiplex Polymerase Chain Reaction
  • Phenotype
  • Proto-Oncogene Proteins c-ets / genetics*
  • Repressor Proteins / genetics*
  • Reverse Transcriptase Polymerase Chain Reaction
  • Translocation, Genetic*

Substances

  • MDS1 and EVI1 Complex Locus Protein
  • MECOM protein, human
  • Proto-Oncogene Proteins c-ets
  • Repressor Proteins

Supplementary concepts

  • Chromosome 7, monosomy