DistributedFBA.jl: high-level, high-performance flux balance analysis in Julia

Bioinformatics. 2017 May 1;33(9):1421-1423. doi: 10.1093/bioinformatics/btw838.

Abstract

Motivation: Flux balance analysis and its variants are widely used methods for predicting steady-state reaction rates in biochemical reaction networks. The exploration of high dimensional networks with such methods is currently hampered by software performance limitations.

Results: DistributedFBA.jl is a high-level, high-performance, open-source implementation of flux balance analysis in Julia. It is tailored to solve multiple flux balance analyses on a subset or all the reactions of large and huge-scale networks, on any number of threads or nodes.

Availability and implementation: The code is freely available on github.com/opencobra/COBRA.jl. The documentation can be found at opencobra.github.io/COBRA.jl.

Contact: ronan.mt.fleming@gmail.com.

Supplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

  • Computational Biology / methods*
  • Metabolic Networks and Pathways*
  • Models, Biological
  • Software*