Abstract
A new DNA polymerase and DNase activity were identified from cells infected with human B-lymphotropic herpesvirus (HBLV). DNA polymerase associated with HBLV infection was similar in its sensitivity to inhibition by ppi analogs as other herpesvirus-specific DNA polymerases but was dissimilar in its inhibition by certain nucleoside triphosphates.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
B-Lymphocytes / microbiology*
-
DNA-Directed DNA Polymerase / isolation & purification
-
DNA-Directed DNA Polymerase / physiology*
-
Deoxyribonucleases / metabolism
-
Herpesviridae / enzymology*
-
Humans
-
Hydrogen-Ion Concentration
-
Kinetics
-
Nucleic Acid Synthesis Inhibitors
-
Nucleotides / pharmacology
-
Potassium Chloride / pharmacology
-
Substrate Specificity
Substances
-
Nucleic Acid Synthesis Inhibitors
-
Nucleotides
-
Potassium Chloride
-
DNA-Directed DNA Polymerase
-
Deoxyribonucleases