Considerations for a European animal welfare standard to evaluate adverse phenotypes in teleost fish
EMBO J. 2016 Jun 1;35(11):1151-4.
doi: 10.15252/embj.201694448.
Epub 2016 Apr 22.
- PMID: 27107050
- PMCID: PMC4888240
- DOI: 10.15252/embj.201694448
Abstract
The EU Directive on the use animals in research requires scientists to assess and document pain, distress or lasting harm of genetically modified animals. This article proposes a detailed protocol and guidelines for assessing adverse phenotypes in teleost fish, an important model organism for biomedical research.
MeSH terms
- Animal Welfare*
- Animals
- Biomedical Research
- Disease Models, Animal
- Europe
- Fishes / genetics*
- Guidelines as Topic
- Humans
- Phenotype