Gastrointestinal stromal tumor as entry port for S. intermedius causing bacteremia and multiple liver abscesses. Case report and review of literature

Z Gastroenterol. 2016 Mar;54(3):245-9. doi: 10.1055/s-0042-100628. Epub 2016 Apr 4.

Abstract

We report a case of a previously healthy 52-year-old man who presented with fever and liver lesions suspicious for metastatic disease, which proved subsequently to be abscesses. Further workup revealed a gastrointestinal stromal tumor (GIST) in the gastric corpus as entry port to Streptococcus intermedius-associated bacteremia and liver abscesses. After antibiotic treatment and surgical resection of the tumor, the patient recovered well. This unusual case indicates that gastrointestinal stromal tumors can remain undetected until they cause a life threatening infection. A review of recent literature pertaining to GIST and liver abscesses follows.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Bacteremia / drug therapy
  • Bacteremia / microbiology*
  • Diagnosis, Differential
  • Gastrointestinal Neoplasms / diagnosis
  • Gastrointestinal Neoplasms / microbiology*
  • Gastrointestinal Stromal Tumors / diagnosis
  • Gastrointestinal Stromal Tumors / microbiology*
  • Humans
  • Liver Abscess, Pyogenic / microbiology*
  • Liver Abscess, Pyogenic / prevention & control
  • Male
  • Middle Aged
  • Penicillin G / administration & dosage
  • Staphylococcal Infections / drug therapy
  • Staphylococcal Infections / microbiology*
  • Staphylococcus intermedius / drug effects
  • Staphylococcus intermedius / isolation & purification*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Penicillin G