Human NUP98-IQCG fusion protein induces acute myelomonocytic leukemia in mice by dysregulating the Hox/Pbx3 pathway

Leukemia. 2016 Jul;30(7):1590-3. doi: 10.1038/leu.2015.347. Epub 2015 Dec 17.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Calmodulin-Binding Proteins / genetics*
  • Cell Transformation, Neoplastic / genetics*
  • Cell Transformation, Neoplastic / metabolism
  • Homeodomain Proteins / metabolism
  • Humans
  • Leukemia, Myelomonocytic, Acute / genetics*
  • Leukemia, Myelomonocytic, Acute / metabolism
  • Mice
  • Nuclear Pore Complex Proteins / genetics*
  • Oncogene Proteins, Fusion / genetics*
  • Proto-Oncogene Proteins / metabolism

Substances

  • Calmodulin-Binding Proteins
  • Homeodomain Proteins
  • Nuclear Pore Complex Proteins
  • Nup98 protein, human
  • Oncogene Proteins, Fusion
  • Proto-Oncogene Proteins
  • proto-oncogene protein Pbx3