FGFR1OP2-FGFR1 induced myeloid leukemia and T-cell lymphoma in a mouse model

MeSH terms

• Animals
• B-Lymphocytes / metabolism
• B-Lymphocytes / pathology
• Bone Marrow / metabolism
• Bone Marrow / pathology
• Bone Marrow Transplantation
• Cytoskeletal Proteins / genetics*
• Cytoskeletal Proteins / metabolism
• Disease Models, Animal
• Gene Expression Regulation, Neoplastic*
• Hematopoietic Stem Cells / metabolism*
• Hematopoietic Stem Cells / pathology
• Humans
• Leukemia, Myeloid, Acute / complications
• Leukemia, Myeloid, Acute / genetics*
• Leukemia, Myeloid, Acute / mortality
• Leukemia, Myeloid, Acute / pathology
• Liver / metabolism
• Liver / pathology
• Lymphoma, T-Cell / complications
• Lymphoma, T-Cell / genetics*
• Lymphoma, T-Cell / mortality
• Lymphoma, T-Cell / pathology
• Membrane Glycoproteins / genetics
• Membrane Glycoproteins / metabolism
• Mice
• Mice, Transgenic
• Oncogene Proteins, Fusion / genetics*
• Oncogene Proteins, Fusion / metabolism
• Proto-Oncogene Proteins c-bcl-2 / genetics
• Proto-Oncogene Proteins c-bcl-2 / metabolism
• Receptor, Fibroblast Growth Factor, Type 1 / genetics*
• Receptor, Fibroblast Growth Factor, Type 1 / metabolism
• Receptor, Notch1 / genetics
• Receptor, Notch1 / metabolism
• Receptor, Notch3 / genetics
• Receptor, Notch3 / metabolism
• Receptors, Antigen, T-Cell, alpha-beta / genetics
• Receptors, Antigen, T-Cell, alpha-beta / metabolism
• Signal Transduction
• Spleen / metabolism
• Spleen / pathology
• Survival Analysis
• T-Lymphocytes / metabolism
• T-Lymphocytes / pathology
• Ubiquitin-Protein Ligases / genetics
• Ubiquitin-Protein Ligases / metabolism
• Whole-Body Irradiation