Wavelength-dependent optoacoustic imaging probes for NMDA receptor visualisation

Chem Commun (Camb). 2015 Oct 21;51(82):15149-52. doi: 10.1039/c5cc06277b.

Abstract

The cellular localisation and binding specificity of two NMDAR-targeted near-IR imaging probes has been examined by microscopy, followed by exemplification of MSOT to monitor simulated glutamate bursts in cellulo and a preliminary study in mice observing the signal in the brain.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cell Line
  • Coordination Complexes / chemistry
  • Europium / chemistry
  • Fluorescent Dyes / chemistry*
  • Glutamic Acid / analysis*
  • Indoles / chemistry*
  • Infrared Rays
  • Mice
  • Photoacoustic Techniques
  • Receptors, N-Methyl-D-Aspartate / analysis*
  • Tomography

Substances

  • Coordination Complexes
  • Fluorescent Dyes
  • Indoles
  • Receptors, N-Methyl-D-Aspartate
  • Glutamic Acid
  • Europium