Frameshift Mutations of CAB39L, an Activator of LKB1 Tumor Suppressor, in Gastric and Colorectal Cancers

Pathol Oncol Res. 2016 Jan;22(1):225-6. doi: 10.1007/s12253-015-9973-0. Epub 2015 Aug 26.

Authors

Mi Ryoung Choi¹, Chang Hyeok An², Nam Jin Yoo¹, Sug Hyung Lee³

Affiliations

¹ Departments of Pathology, College of Medicine, The Catholic University of Korea, 505 Banpo-dong, Socho-gu, Seoul, 137-701, South Korea.
² General Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
³ Departments of Pathology, College of Medicine, The Catholic University of Korea, 505 Banpo-dong, Socho-gu, Seoul, 137-701, South Korea. suhulee@catholic.ac.kr.

PMID: 26306467
DOI: 10.1007/s12253-015-9973-0

No abstract available

Keywords: CAB39L; LKB1; STK24; cancers; microsatellite instability; mutation.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

AMP-Activated Protein Kinase Kinases
Antigens, Neoplasm / genetics*
Apoptosis Regulatory Proteins / genetics*
Colorectal Neoplasms / genetics*
Frameshift Mutation / genetics*
Genes, Tumor Suppressor
Humans
Microsatellite Instability
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Prognosis
Protein Serine-Threonine Kinases / genetics*
Stomach Neoplasms / genetics*

Substances

Antigens, Neoplasm
Apoptosis Regulatory Proteins
CAB39L protein, human
Protein Serine-Threonine Kinases
STK11 protein, human
AMP-Activated Protein Kinase Kinases