Chromosomal localization of the human homeo box-containing genes, EN1 and EN2

C Logan; H F Willard; J M Rommens; A L Joyner

doi:10.1016/0888-7543(89)90301-7

Chromosomal localization of the human homeo box-containing genes, EN1 and EN2

Genomics. 1989 Feb;4(2):206-9. doi: 10.1016/0888-7543(89)90301-7.

Authors

C Logan¹, H F Willard, J M Rommens, A L Joyner

Affiliation

¹ Division of Molecular and Developmental Biology, Mount Sinai Hospital Research Institute, Toronto, Ontario, Canada.

PMID: 2567700
DOI: 10.1016/0888-7543(89)90301-7

Abstract

The human homologs of the mouse homeo box-containing genes, En-1 and En-2, which show homology to the Drosophila engrailed gene, have been isolated. The human EN1 gene was mapped to chromosome 2 by analysis of mouse-human somatic cell hybrids. The human EN2 gene was localized to chromosome 7, 7q32-7qter, by analysis of rodent-human somatic cell hybrids and cell lines carrying portions of chromosome 7.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Blotting, Southern
Chromosome Mapping
Chromosomes, Human, Pair 2*
Chromosomes, Human, Pair 7*
Genes, Homeobox*
Humans
Hybrid Cells
Mice