Aim: The aim of this study was to make immunohistochemical analyses with Inhibin alpha-subunit, Melan A and MNF116 (pan-Cytokeratin antibody) in pheochromocytomas, because immunohistochemistry is useful for the distinction between adrenal tumors.
Patients and methods: We used 20 patients with pheochromocytomas submitted to laparoscopic (n=19) or classical (n=1) surgery and we have explored immuno-staining with Inhibin alpha-subunit, Melan A and MNF116 in these tumors. This can be helpful when we cannot make the distinction between adrenal tumors.
Results: Pheochromocytomas did not stain with Inhibin alpha-subunit, Melan A and MNF116.
Conclusions: In our study, Inhibin alpha-subunit, Melan A and MNF116 were not sensitive for pheochromocytomas.