Transglutaminase 3 present in the IgA aggregates in dermatitis herpetiformis skin is enzymatically active and binds soluble fibrinogen

J Invest Dermatol. 2015 Feb;135(2):623-625. doi: 10.1038/jid.2014.368. Epub 2014 Sep 1.

Authors

Ted B Taylor¹, Linda A Schmidt¹, Laurence J Meyer², John J Zone³

Affiliations

¹ Department of Dermatology, University of Utah, Salt Lake City, Utah, USA.
² Department of Dermatology, University of Utah, Salt Lake City, Utah, USA; Veterans Administration Hospital, Salt Lake City, Utah, USA.
³ Department of Dermatology, University of Utah, Salt Lake City, Utah, USA. Electronic address: john.zone@hsc.utah.edu.

PMID: 25178107
DOI: 10.1038/jid.2014.368

No abstract available

Publication types

Letter

MeSH terms

Dermatitis Herpetiformis / metabolism*
Fibrinogen / metabolism*
Humans
Immunoglobulin A / chemistry*
Protein Aggregates*
Skin / enzymology*
Transglutaminases / chemistry
Transglutaminases / metabolism*

Substances

Immunoglobulin A
Protein Aggregates
Fibrinogen
TGM3 protein, human
Transglutaminases