Sequence and expression of human GABAA receptor al...[FEBS Lett. 1989]

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1: FEBS Lett. 1989 Feb 27;244(2):361-4. Links

Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits.

Schofield PR, Pritchett DB, Sontheimer H, Kettenmann H, Seeburg PH.

Zentrum für Molekulare Biologie, University of Heidelberg, FRG.

The deduced amino acid sequences of cDNA clones encoding human GABAA receptor alpha 1 and beta 1 subunits are presented. The human subunits display very high levels of sequence identity with the corresponding bovine receptor subunits. The cloned human GABAA receptor subunits induce the formation of GABA-gated chloride channels when expressed in mammalian cells.

PMID: 2465923 [PubMed - indexed for MEDLINE]

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ReviewPharmacologic significance of the structural heterogeneity of the GABAA receptor-chloride ion channel complex. [Neuropsychopharmacology. 1991]
Review[Structure and function of gamma-aminobutyric acid (GABA) receptor: current state and prospectives] [Nippon Yakurigaku Zasshi. 1989]

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Sequence and expression of human GABAA receptor alpha 1 and beta 1 subunits.

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