[The proinsulin level in the blood of children with type 1 diabetes mellitus of various duration]

Biomed Khim. 2013 Sep-Oct;59(5):563-9. doi: 10.18097/pbmc20135905563.
[Article in Russian]

Abstract

Proinsulin content was measured in the serum of 82 children (aged from 3 to 14 years) with type 1 diabetes mellitus of various duration. Three groups of patients characterized by low (54%), normal (42%) and high (4%) levels of this prohormone were recognized. No dependence the proinsulin level on the disease term was found. The serum proinsulin level may be used as a parameter specifying the pathogenesis of type 1 diabetes mellitus.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Biomarkers / blood
  • Child
  • Child, Preschool
  • Diabetes Mellitus, Type 1 / blood*
  • Female
  • Humans
  • Male
  • Proinsulin / blood*
  • Time Factors

Substances

  • Biomarkers
  • Proinsulin