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Peroxisomal multifunctional protein-2 deficiency causes neuroinflammation and degeneration of Purkinje cells independent of very long chain fatty acid accumulation.
Neurobiol Dis. 2013 Oct;58:258-69. doi: 10.1016/j.nbd.2013.06.006. Epub 2013 Jun 15.
Neurobiol Dis. 2013.
PMID: 23777740
Inactivation of the peroxisomal multifunctional protein-2 in mice impedes the degradation of not only 2-methyl-branched fatty acids and bile acid intermediates but also of very long chain fatty acids.
Baes M, Huyghe S, Carmeliet P, Declercq PE, Collen D, Mannaerts GP, Van Veldhoven PP.
Baes M, et al.
J Biol Chem. 2000 May 26;275(21):16329-36. doi: 10.1074/jbc.M001994200.
J Biol Chem. 2000.
PMID: 10748062
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