Crystallization of blood coagulation factor XIII by an automated procedure

FEBS Lett. 1990 Jun 4;265(1-2):110-2. doi: 10.1016/0014-5793(90)80896-q.

Abstract

Both recombinant blood coagulation factor XIII alpha-chain and factor XIII isolated from human placenta have been crystallized using a novel robotic system for the automatic screening of crystallization conditions. The monoclinic and orthorhombic crystals obtained are suitable for X-ray analysis.

MeSH terms

  • Crystallization
  • Enzyme Precursors / isolation & purification
  • Factor XIII / isolation & purification*
  • Female
  • Humans
  • Placenta / enzymology
  • Pregnancy
  • X-Ray Diffraction

Substances

  • Enzyme Precursors
  • Factor XIII