B1+-mapping with the transient phase of unbalanced steady-state free precession

Magn Reson Med. 2013 Dec;70(6):1515-23. doi: 10.1002/mrm.24598. Epub 2013 Feb 4.

Abstract

Purpose: A novel B1+-mapping technique (B1-TRAP) is presented, which derives the actual flip angle from the frequency of signal oscillations, observed in the transient phase of unbalanced steady-state free precession sequences.

Theory: For short repetition times (TR), the angular frequency of distinct oscillations in the transient phase of steady-state free precession sequences is proven to be approximately proportional to the actual flip angle: ω⋅TR≈α. The result is not influenced by off-resonance and it can be shown that deviations are only of second order in the small parameter TR/T2.

Methods: B1-TRAP makes use of this effect through a frequency analysis of the transient phase of a train of steady-state free precession signals.

Results: In terms of reliability and time efficiency, a two-dimensional multislice implementation was found to be optimal. Unlike many steady-state B1+-mapping methods, the accuracy of B1-TRAP was not impaired by imperfect slice profiles.

Conclusion: Simulations, phantom, and in vivo measurements showed that B1-TRAP offers a good compromise with respect to speed, robustness, and accuracy.

Keywords: B1-mapping; SSFP; actual flip angle; off-resonance; transient phase.

MeSH terms

  • Algorithms*
  • Brain / anatomy & histology*
  • Brain Mapping / methods*
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Magnetic Resonance Imaging / instrumentation
  • Magnetic Resonance Imaging / methods*
  • Phantoms, Imaging
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted*