[Serum A1-antitrypsin levels in prostate pathology]

Urologiia. 2012 Sep-Oct:(5):77-80.
[Article in Russian]

Abstract

The serum alpha1-antitrypsin (AAT) levels were determined using enzyme-linked immunosorbent assay (ELISA) and turbidimetry in patients with prostate cancer, patients with benign prostatic hyperplasia and healthy volunteers. Both methods revealed a significant increase of serum AAT levels in patients with prostate cancer compared with patients with BPH and healthy men. ELISA, as used in study, was more sensitive to changes in the concentration of AAT, but the sensitivity of the turbidimetry allows to use this method in the early diagnosis of prostate cancer.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Enzyme-Linked Immunosorbent Assay / methods
  • Humans
  • Male
  • Middle Aged
  • Prostatic Hyperplasia / blood*
  • Prostatic Neoplasms / blood*
  • Sensitivity and Specificity
  • alpha 1-Antitrypsin / blood*

Substances

  • alpha 1-Antitrypsin