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The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain.
J Exp Med. 2013 Jan 14;210(1):41-58. doi: 10.1084/jem.20121069. Epub 2012 Dec 24.
J Exp Med. 2013.
PMID: 23267015
Free PMC article.
The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain.
Beisner DR, Langerak P, Parker AE, Dahlberg C, Otero FJ, Sutton SE, Poirot L, Barnes W, Young MA, Niessen S, Wiltshire T, Bodendorf U, Martoglio B, Cravatt B, Cooke MP.
Beisner DR, et al.
J Exp Med. 2013 Jan 14;210(1):23-30. doi: 10.1084/jem.20121072. Epub 2012 Dec 24.
J Exp Med. 2013.
PMID: 23267013
Free PMC article.
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