Two consecutive open heart operations in a small child with heparin-induced thrombocytopenia type II using anticoagulation with heparin and tirofiban

Ann Thorac Surg. 2012 Aug;94(2):653-5. doi: 10.1016/j.athoracsur.2011.12.091. Epub 2012 May 10.

Abstract

We report the use of the platelet glycoprotein IIb/IIIa antagonist tirofiban for cardiac surgery in a small child with active heparin-induced thrombocytopenia type II, including description of the postoperative course.

Publication types

  • Case Reports

MeSH terms

  • Anticoagulants / adverse effects*
  • Anticoagulants / therapeutic use
  • Body Size
  • Cardiac Surgical Procedures* / methods
  • Drug Therapy, Combination
  • Heart Septal Defects / complications
  • Heart Septal Defects / surgery*
  • Heparin / adverse effects*
  • Heparin / therapeutic use
  • Humans
  • Infant
  • Male
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Thrombocytopenia / chemically induced*
  • Thrombocytopenia / classification
  • Tirofiban
  • Tyrosine / analogs & derivatives*
  • Tyrosine / therapeutic use

Substances

  • Anticoagulants
  • Platelet Aggregation Inhibitors
  • Tyrosine
  • Heparin
  • Tirofiban