[Pathology and classification of intraductal papillary mucinous neoplasms of the pancreas]

A M Schlitter; I Esposito

doi:10.1007/s00104-011-2181-x

[Pathology and classification of intraductal papillary mucinous neoplasms of the pancreas]

Chirurg. 2012 Feb;83(2):110-5. doi: 10.1007/s00104-011-2181-x.

[Article in German]

Authors

A M Schlitter¹, I Esposito

Affiliation

¹ Institut für Pathologie, Technische Universität München, Ismaninger Strasse 22, Munich, Germany.

PMID: 22271052
DOI: 10.1007/s00104-011-2181-x

Abstract

Intraductal papillary mucinous neoplasms (IPMN) are precursor lesions of ductal adenocarcinoma of the pancreas and one of the most common cystic entities in this organ. Branch and main duct types are further distinguished based on the tumor localization. An additional classification is based on the predominant architecture and immunohistochemical profile with four prognostic relevant subtypes, gastric, intestinal, pancreato-biliary and oncocytic. This review provides an overview about the malignant potential of the different subtypes and the prognosis of associated invasive tumors and gives recommendations for the pathological assessment of resection specimens with IPMNs.

Publication types

English Abstract
Review

MeSH terms

Carcinoma, Pancreatic Ductal / classification*
Carcinoma, Pancreatic Ductal / epidemiology
Carcinoma, Pancreatic Ductal / pathology*
Carcinoma, Pancreatic Ductal / surgery
Cell Transformation, Neoplastic / pathology
Cross-Sectional Studies
Diagnosis, Differential
Female
Humans
Incidental Findings
Male
Neoplasm Invasiveness
Pancreas / pathology
Pancreas / surgery
Pancreatic Ducts / pathology
Pancreatic Ducts / surgery
Pancreatic Neoplasms / classification*
Pancreatic Neoplasms / epidemiology
Pancreatic Neoplasms / pathology*
Pancreatic Neoplasms / surgery
Precancerous Conditions / classification
Precancerous Conditions / epidemiology
Precancerous Conditions / pathology
Precancerous Conditions / surgery
Prognosis
Sex Factors