Assignment of the human nicotinic acetylcholine receptor genes: the alpha and delta subunit genes to chromosome 2 and the beta subunit gene to chromosome 17

D Beeson; S Jeremiah; L F West; S Povey; J Newsom-Davis

doi:10.1111/j.1469-1809.1990.tb00378.x

Assignment of the human nicotinic acetylcholine receptor genes: the alpha and delta subunit genes to chromosome 2 and the beta subunit gene to chromosome 17

Ann Hum Genet. 1990 Jul;54(3):199-208. doi: 10.1111/j.1469-1809.1990.tb00378.x.

Authors

D Beeson¹, S Jeremiah, L F West, S Povey, J Newsom-Davis

Affiliation

¹ Institute for Molecular Medicine, John Radcliffe Hospital, Oxford.

PMID: 2221824
DOI: 10.1111/j.1469-1809.1990.tb00378.x

Abstract

The chromosomal assignments of the genes coding for the alpha, beta and delta subunits of the human nicotinic acetylcholine receptor have been determined from a panel of somatic cell hybrids and by direct in situ hybridization. The results localize CHRNA to 2q24-2q32. CHRNB to 17p11-17p12, and CHRND to chromosome 2q33-2qter.

MeSH terms

Animals
Blotting, Southern
Chromosome Mapping
Chromosomes, Human, Pair 17*
Chromosomes, Human, Pair 2*
DNA Probes
Humans
Hybrid Cells
Receptors, Nicotinic / genetics*

Substances

DNA Probes
Receptors, Nicotinic