Abstract
Emetine is still an important agent for the treatment of invasive intestinal amebiasis and amebic liver abscess. Its most relevant side effect is its well documented cardiotoxicity. The authors review the hypotheses that have been suggested concerning the mechanism of this cardiotoxic action.
MeSH terms
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Animals
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Emetine / adverse effects*
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Emetine / pharmacology
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Heart / drug effects*
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Heart / physiopathology
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Humans
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Muscle Proteins / metabolism
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Myocardium / metabolism
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Myocardium / pathology
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Protein Synthesis Inhibitors / pharmacology
Substances
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Muscle Proteins
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Protein Synthesis Inhibitors
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Emetine