A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study

Mol Psychiatry. 2011 Jun;16(6):584-5. doi: 10.1038/mp.2011.1. Epub 2011 Feb 22.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Intramural

MeSH terms

  • Adolescent
  • Adult
  • Benzylamines / pharmacokinetics
  • Bipolar Disorder / genetics
  • Brain Mapping
  • Carbohydrate Epimerases / genetics*
  • Carbon Isotopes / pharmacokinetics
  • Depressive Disorder, Major / genetics
  • Female
  • Genome-Wide Association Study
  • Humans
  • Magnetic Resonance Imaging / methods
  • Male
  • Middle Aged
  • Polymorphism, Single Nucleotide / genetics*
  • Positron-Emission Tomography
  • Protein Binding / drug effects
  • Protein Binding / genetics
  • Serotonin Plasma Membrane Transport Proteins / genetics
  • Serotonin Plasma Membrane Transport Proteins / metabolism*
  • Thalamus / diagnostic imaging
  • Thalamus / metabolism*
  • Young Adult

Substances

  • Benzylamines
  • Carbon Isotopes
  • N,N-dimethyl-2-(2-amino-4-cyanophenylthio)benzylamine
  • Serotonin Plasma Membrane Transport Proteins
  • Carbohydrate Epimerases
  • galactose mutarotase