A systematic search for endoplasmic reticulum (ER) membrane-associated RING finger proteins identifies Nixin/ZNRF4 as a regulator of calnexin stability and ER homeostasis

Affiliations

• ¹ From the Biochemistry Section, Surgical Neurological Branch, NINDS, National Institutes of Health, Bethesda, Maryland 20892,; the Department of Biomedicine, and the University Eye Clinic, University Hospital Basel, Hebelstrasse 20, 4031 Basel, Switzerland,. Electronic address: albert.neutzner@unibas.ch.
• ² the Department of Biomedicine, and the University Eye Clinic, University Hospital Basel, Hebelstrasse 20, 4031 Basel, Switzerland,; the Department of Neuropathology, Institute of Pathology, University of Basel, Schönbeinstrasse 40, 4031 Basel, Switzerland.
• ³ the Department of Biomedicine, and the University Eye Clinic, University Hospital Basel, Hebelstrasse 20, 4031 Basel, Switzerland.
• ⁴ From the Biochemistry Section, Surgical Neurological Branch, NINDS, National Institutes of Health, Bethesda, Maryland 20892,; the Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon 305-701, South Korea, and.
• ⁵ the Department of Neuropathology, Institute of Pathology, University of Basel, Schönbeinstrasse 40, 4031 Basel, Switzerland.
• ⁶ From the Biochemistry Section, Surgical Neurological Branch, NINDS, National Institutes of Health, Bethesda, Maryland 20892.
• ⁷ From the Biochemistry Section, Surgical Neurological Branch, NINDS, National Institutes of Health, Bethesda, Maryland 20892,; the Center for Biomedical Engineering and Technology and Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland 21201. Electronic address: mkarbowski@umaryland.edu.