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Mouse ataxin-3 functional knock-out model.
Neuromolecular Med. 2011 Mar;13(1):54-65. doi: 10.1007/s12017-010-8137-3. Epub 2010 Oct 14.
Neuromolecular Med. 2011.
PMID: 20945165
Free PMC article.
Inactivation of the mouse Atxn3 (ataxin-3) gene increases protein ubiquitination.
Schmitt I, Linden M, Khazneh H, Evert BO, Breuer P, Klockgether T, Wuellner U.
Schmitt I, et al.
Biochem Biophys Res Commun. 2007 Oct 26;362(3):734-9. doi: 10.1016/j.bbrc.2007.08.062. Epub 2007 Aug 23.
Biochem Biophys Res Commun. 2007.
PMID: 17764659
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A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD.
Switonski PM, Szlachcic WJ, Krzyzosiak WJ, Figiel M.
Switonski PM, et al.
Neurobiol Dis. 2015 Jan;73:174-88. doi: 10.1016/j.nbd.2014.09.020. Epub 2014 Oct 7.
Neurobiol Dis. 2015.
PMID: 25301414
Free article.
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Comparison of spinocerebellar ataxia type 3 mouse models identifies early gain-of-function, cell-autonomous transcriptional changes in oligodendrocytes.
Ramani B, Panwar B, Moore LR, Wang B, Huang R, Guan Y, Paulson HL.
Ramani B, et al.
Hum Mol Genet. 2017 Sep 1;26(17):3362-3374. doi: 10.1093/hmg/ddx224.
Hum Mol Genet. 2017.
PMID: 28854700
Free PMC article.
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