MicroRNAs and cellular phenotypy

Kenneth S Kosik

doi:10.1016/j.cell.2010.09.008

MicroRNAs and cellular phenotypy

Cell. 2010 Oct 1;143(1):21-6. doi: 10.1016/j.cell.2010.09.008.

Author

Kenneth S Kosik¹

Affiliation

¹ Neuroscience Research Institute, Department of Molecular Cellular Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA. kenneth.kosik@lifesci.ucsb.edu

PMID: 20887887
DOI: 10.1016/j.cell.2010.09.008

Abstract

This Essay explores the notion that specialized cells have unique vulnerabilities to environmental contingencies that microRNAs help to counteract. Given the ease with which new microRNAs evolve, they may serve as ideal facilitators for the emergence of new cell types.

MeSH terms

Animals
Cell Differentiation
Gene Expression Profiling*
Gene Expression Regulation
Humans
MicroRNAs / genetics*
Phenotype

Substances

MicroRNAs