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HNF-1 alpha and HNF-1 beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro.
Genes Dev. 1991 Jun;5(6):1042-56. doi: 10.1101/gad.5.6.1042.
Genes Dev. 1991.
PMID: 2044952
Free article.
Molecular cloning, functional expression, and chromosomal localization of mouse hepatocyte nuclear factor 1.
Kuo CJ, Conley PB, Hsieh CL, Francke U, Crabtree GR.
Kuo CJ, et al.
Proc Natl Acad Sci U S A. 1990 Dec;87(24):9838-42. doi: 10.1073/pnas.87.24.9838.
Proc Natl Acad Sci U S A. 1990.
PMID: 2263635
Free PMC article.
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A molecular link between the common phenotypes of type 1 glycogen storage disease and HNF1alpha-null mice.
Hiraiwa H, Pan CJ, Lin B, Akiyama TE, Gonzalez FJ, Chou JY.
Hiraiwa H, et al.
J Biol Chem. 2001 Mar 16;276(11):7963-7. doi: 10.1074/jbc.M010523200. Epub 2000 Dec 19.
J Biol Chem. 2001.
PMID: 11121425
Free article.
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HNF1alpha controls renal glucose reabsorption in mouse and man.
Pontoglio M, Prié D, Cheret C, Doyen A, Leroy C, Froguel P, Velho G, Yaniv M, Friedlander G.
Pontoglio M, et al.
EMBO Rep. 2000 Oct;1(4):359-65. doi: 10.1093/embo-reports/kvd071.
EMBO Rep. 2000.
PMID: 11269503
Free PMC article.
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Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism.
Shih DQ, Bussen M, Sehayek E, Ananthanarayanan M, Shneider BL, Suchy FJ, Shefer S, Bollileni JS, Gonzalez FJ, Breslow JL, Stoffel M.
Shih DQ, et al.
Nat Genet. 2001 Apr;27(4):375-82. doi: 10.1038/86871.
Nat Genet. 2001.
PMID: 11279518
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Hepatocyte nuclear factor 1 alpha controls renal expression of the Npt1-Npt4 anionic transporter locus.
Cheret C, Doyen A, Yaniv M, Pontoglio M.
Cheret C, et al.
J Mol Biol. 2002 Oct 4;322(5):929-41. doi: 10.1016/s0022-2836(02)00816-1.
J Mol Biol. 2002.
PMID: 12367519
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Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice.
Hiesberger T, Bai Y, Shao X, McNally BT, Sinclair AM, Tian X, Somlo S, Igarashi P.
Hiesberger T, et al.
J Clin Invest. 2004 Mar;113(6):814-25. doi: 10.1172/JCI20083.
J Clin Invest. 2004.
PMID: 15067314
Free PMC article.
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