A novel mutation adjacent to the Bth mouse mutation in the TMC1 gene makes this mouse an excellent model of human deafness at the DFNA36 locus

Clin Genet. 2010 Apr;77(4):395-8. doi: 10.1111/j.1399-0004.2009.01338.x.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Audiometry
  • Base Sequence
  • Chromosome Segregation / genetics
  • DNA Mutational Analysis
  • Deafness / genetics*
  • Disease Models, Animal*
  • Family
  • Female
  • Genetic Loci / genetics*
  • Humans
  • Male
  • Membrane Proteins / chemistry
  • Membrane Proteins / genetics*
  • Mice
  • Molecular Sequence Data
  • Mutation / genetics*
  • Pedigree

Substances

  • Membrane Proteins
  • TMC1 protein, human