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In vitro-in vivo correlation for intrinsic clearance for drugs metabolized by human aldehyde oxidase.
Drug Metab Dispos. 2010 Aug;38(8):1322-7. doi: 10.1124/dmd.110.033555. Epub 2010 May 5.
Drug Metab Dispos. 2010.
PMID: 20444863
Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes.
Hutzler JM, Yang YS, Albaugh D, Fullenwider CL, Schmenk J, Fisher MB.
Hutzler JM, et al.
Drug Metab Dispos. 2012 Feb;40(2):267-75. doi: 10.1124/dmd.111.042861. Epub 2011 Oct 26.
Drug Metab Dispos. 2012.
PMID: 22031625
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Hydralazine as a selective probe inactivator of aldehyde oxidase in human hepatocytes: estimation of the contribution of aldehyde oxidase to metabolic clearance.
Strelevitz TJ, Orozco CC, Obach RS.
Strelevitz TJ, et al.
Drug Metab Dispos. 2012 Jul;40(7):1441-8. doi: 10.1124/dmd.112.045195. Epub 2012 Apr 20.
Drug Metab Dispos. 2012.
PMID: 22522748
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Aldehyde oxidase 1 (AOX1) in human liver cytosols: quantitative characterization of AOX1 expression level and activity relationship.
Fu C, Di L, Han X, Soderstrom C, Snyder M, Troutman MD, Obach RS, Zhang H.
Fu C, et al.
Drug Metab Dispos. 2013 Oct;41(10):1797-804. doi: 10.1124/dmd.113.053082. Epub 2013 Jul 15.
Drug Metab Dispos. 2013.
PMID: 23857892
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