Crystal structure of a cisplatin-(1,3-GTG) cross-link within DNA polymerase eta

Angew Chem Int Ed Engl. 2010 Apr 12;49(17):3077-80. doi: 10.1002/anie.201000414.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology
  • Cisplatin / chemistry*
  • Cisplatin / pharmacology*
  • Cross-Linking Reagents / chemistry*
  • Cross-Linking Reagents / pharmacology*
  • Crystallography, X-Ray
  • DNA-Directed DNA Polymerase / chemistry*
  • DNA-Directed DNA Polymerase / metabolism
  • Humans
  • Neoplasms / drug therapy
  • Saccharomyces cerevisiae / enzymology*

Substances

  • Antineoplastic Agents
  • Cross-Linking Reagents
  • DNA-Directed DNA Polymerase
  • Rad30 protein
  • Cisplatin