Primary structure of a human protein kinase regulator protein

Biochim Biophys Acta. 1991 Mar 26;1088(3):425-8. doi: 10.1016/0167-4781(91)90136-a.

Abstract

A human T-cell cDNA is characterized which codes for a protein closely related to a family of proteins alternatively described as co-regulators, of monoamine biosynthesis in neurons and as inhibitors of protein kinase C. The predicted human protein is 28 kDa and has a pI of 4.5. Alignment of putative protein sequences shows strong conservation from Drosophila to man. Several mRNA transcripts hybridizing to the cDNA are seen in human epithelial and T-cell lines and in various mouse tissues.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Blotting, Northern
  • Blotting, Southern
  • Carrier Proteins / genetics*
  • Cattle
  • Cell Line
  • DNA / genetics
  • Humans
  • Intracellular Signaling Peptides and Proteins*
  • Mice
  • Molecular Sequence Data
  • Protein Kinases / genetics*
  • RNA, Messenger / genetics
  • Sequence Alignment
  • Transcription, Genetic

Substances

  • Carrier Proteins
  • Intracellular Signaling Peptides and Proteins
  • RNA, Messenger
  • protein kinase modulator
  • DNA
  • Protein Kinases

Associated data

  • GENBANK/M75971
  • GENBANK/M75972
  • GENBANK/M75973
  • GENBANK/M75974
  • GENBANK/M75975
  • GENBANK/S57579
  • GENBANK/S59357
  • GENBANK/X54747
  • GENBANK/X54748
  • GENBANK/X56468