How much more effective do depot antipsychotics have to be compared to oral antipsychotics before they are prescribed?

Eur Neuropsychopharmacol. 2010 Apr;20(4):276-9. doi: 10.1016/j.euroneuro.2010.01.001. Epub 2010 Feb 4.

Abstract

Antipsychotic depots are less frequently prescribed than oral compounds. In an experimental study involving N=106 psychiatrists we studied how much more effective with respect to relapse prevention depot antipsychotics have to be compared to oral antipsychotics before they are chosen for prescription. Most psychiatrists have to judge depot as clearly superior with respect to relapse prevention before they recommend it to patients. If psychiatrists judge depot as unpleasant for the patients and do not see much need for checking their patients' compliance they are less likely to prescribe depot. Other psychiatrist-related factors (e.g. age, gender, and work experience) did not influence attitudes toward depot.

Publication types

  • Comparative Study

MeSH terms

  • Administration, Oral
  • Antipsychotic Agents / administration & dosage*
  • Attitude of Health Personnel*
  • Choice Behavior
  • Delayed-Action Preparations
  • Female
  • Health Care Surveys / methods
  • Humans
  • Male
  • Middle Aged
  • Practice Patterns, Physicians' / statistics & numerical data*
  • Psychiatry / statistics & numerical data

Substances

  • Antipsychotic Agents
  • Delayed-Action Preparations