Alternative splicing and gene polymorphism of the human TAP3/SEC14L4 gene

Petra Kempna; Roberta Ricciarelli; Angelo Azzi; Jean-Marc Zingg

doi:10.1007/s11033-009-9943-2

Alternative splicing and gene polymorphism of the human TAP3/SEC14L4 gene

Mol Biol Rep. 2010 Oct;37(7):3503-8. doi: 10.1007/s11033-009-9943-2. Epub 2009 Dec 10.

Authors

Petra Kempna¹, Roberta Ricciarelli, Angelo Azzi, Jean-Marc Zingg

Affiliation

¹ Department of Pediatric Endocrinology and Diabetology, University Children's Hospital, Bern, Switzerland.

PMID: 20012369
DOI: 10.1007/s11033-009-9943-2

Abstract

Three closely related human SEC14p-like proteins (hTAP1, hTAP2, hTAP3, or SEC14L2, SEC14L3, SEC14L4, respectively) have been described that are related to the Saccharomyces cerevisiae SEC14 protein. These proteins may participate in intracellular lipid transport and influence regulatory lipid-dependent events. Here we report the isolation of an alternatively spliced hTAP3 cDNA and a polymorphism within the coding region of the hTAP3/SEC14L4 gene.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alternative Splicing / genetics*
Base Sequence
Carrier Proteins / genetics*
Exons / genetics
Humans
Introns / genetics
Molecular Sequence Data
Organ Specificity / genetics
Polymorphism, Single Nucleotide / genetics*
Proteins / genetics*
RNA, Messenger / genetics
RNA, Messenger / metabolism
Sequence Alignment

Substances

Carrier Proteins
Proteins
RNA, Messenger
SEC14L4 protein, human