Induction of histone acetylation on the sucrase-isomaltase gene in the postnatal rat jejunum

Biosci Biotechnol Biochem. 2009 Apr 23;73(4):933-5. doi: 10.1271/bbb.80719. Epub 2009 Apr 7.

Abstract

The rapid induction of the sucrase-isomaltase (SI) gene in rat jejunum from the onset to final period of weaning was associated with increases of the acetylation of histones H3 and H4 on the promoter/transcriptional region of the gene, suggesting that an abrupt jejunal induction of histone acetylation changes on the SI gene during this period may be concerned with the expression of the gene.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetylation
  • Animals
  • Female
  • Gene Expression Regulation, Developmental
  • Histones / metabolism*
  • Jejunum / metabolism*
  • Rats
  • Rats, Sprague-Dawley
  • Sucrase-Isomaltase Complex / genetics*
  • Transcriptional Activation*

Substances

  • Histones
  • Sucrase-Isomaltase Complex