Life-threatening complications associated with acute monocytic leukaemia after dental treatment

Aust Dent J. 2009 Mar;54(1):45-8. doi: 10.1111/j.1834-7819.2008.01087.x.

Abstract

It is highly recommended to conduct a prophylactic check for any dental problems on patients who suffer from leukaemia before chemotherapy begins. Bacteraemia caused by oral microflora may be very dangerous for patients with haematological malignancies. However, it should be noted that the prophylactic process itself might bring about life-threatening complications if there is only a short interval between dental treatment and the beginning of chemotherapy, or if the dental treatment is too aggressive. We present a case where this prophylactic procedure produced life-threatening complications for a patient with acute myeloid leukaemia.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bacteremia / complications
  • Bacteremia / etiology*
  • Bacteremia / microbiology
  • Blast Crisis / complications*
  • Enterobacter cloacae
  • Enterobacteriaceae Infections / complications*
  • Enterobacteriaceae Infections / drug therapy
  • Fatal Outcome
  • Graft vs Host Disease / etiology
  • Humans
  • Jaw Diseases / complications
  • Leukemia, Monocytic, Acute / complications*
  • Leukemia, Monocytic, Acute / drug therapy
  • Male
  • Osteonecrosis / complications
  • Sepsis / etiology
  • Stem Cell Transplantation / adverse effects
  • Tooth Extraction / adverse effects*
  • Vancomycin / therapeutic use
  • Vancomycin Resistance

Substances

  • Anti-Bacterial Agents
  • Vancomycin