A 10-year survey of antifungal susceptibility of candidemia isolates from intensive care unit patients in Greece

George Dimopoulos; Aristea Velegraki; Matthew E Falagas

doi:10.1128/AAC.01368-08

A 10-year survey of antifungal susceptibility of candidemia isolates from intensive care unit patients in Greece

Antimicrob Agents Chemother. 2009 Mar;53(3):1242-4. doi: 10.1128/AAC.01368-08. Epub 2008 Dec 29.

Authors

George Dimopoulos¹, Aristea Velegraki, Matthew E Falagas

Affiliation

¹ Department of Critical Care, University Hospital Attikon, Medical School, National and Kapodistrian Univeristy of Athens, Athens, Greece.

Abstract

This study retrospectively reviews the susceptibility of 135 baseline ICU candidemia isolates (from 1997 to 2007) to nine antifungals as determined by the AFST-EUCAST microdilution method and identifies the most frequent causative agents of confirmed point-source candidemia outbreaks in local intensive care units. A minority of common and rare Candida species displayed decreased susceptibility to all antifungals.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antifungal Agents / pharmacology*
Antifungal Agents / therapeutic use
Candida / classification
Candida / drug effects*
Candida / isolation & purification
Candidiasis / blood
Candidiasis / drug therapy*
Candidiasis / epidemiology*
Candidiasis / microbiology
Data Collection*
Disease Susceptibility
Greece / epidemiology
Humans
Intensive Care Units
Microbial Sensitivity Tests / methods
Retrospective Studies

Substances

Antifungal Agents