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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2008 | 1 |
2014 | 3 |
2015 | 3 |
2016 | 2 |
2024 | 0 |
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7 results
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Page 1
p53 target genes sestrin1 and sestrin2 connect genotoxic stress and mTOR signaling.
Cell. 2008 Aug 8;134(3):451-60. doi: 10.1016/j.cell.2008.06.028.
Cell. 2008.
PMID: 18692468
Free PMC article.
Hepatoprotective role of Sestrin2 against chronic ER stress.
Park HW, Park H, Ro SH, Jang I, Semple IA, Kim DN, Kim M, Nam M, Zhang D, Yin L, Lee JH.
Park HW, et al.
Nat Commun. 2014 Jun 20;5:4233. doi: 10.1038/ncomms5233.
Nat Commun. 2014.
PMID: 24947615
Free PMC article.
Item in Clipboard
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1.
Chantranupong L, Wolfson RL, Orozco JM, Saxton RA, Scaria SM, Bar-Peled L, Spooner E, Isasa M, Gygi SP, Sabatini DM.
Chantranupong L, et al.
Cell Rep. 2014 Oct 9;9(1):1-8. doi: 10.1016/j.celrep.2014.09.014. Epub 2014 Sep 25.
Cell Rep. 2014.
PMID: 25263562
Free PMC article.
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Sestrins inhibit mTORC1 kinase activation through the GATOR complex.
Parmigiani A, Nourbakhsh A, Ding B, Wang W, Kim YC, Akopiants K, Guan KL, Karin M, Budanov AV.
Parmigiani A, et al.
Cell Rep. 2014 Nov 20;9(4):1281-91. doi: 10.1016/j.celrep.2014.10.019.
Cell Rep. 2014.
PMID: 25457612
Free PMC article.
Item in Clipboard
Sestrin2 is a leucine sensor for the mTORC1 pathway.
Wolfson RL, Chantranupong L, Saxton RA, Shen K, Scaria SM, Cantor JR, Sabatini DM.
Wolfson RL, et al.
Science. 2016 Jan 1;351(6268):43-8. doi: 10.1126/science.aab2674. Epub 2015 Oct 8.
Science. 2016.
PMID: 26449471
Free PMC article.
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Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway.
Saxton RA, Knockenhauer KE, Wolfson RL, Chantranupong L, Pacold ME, Wang T, Schwartz TU, Sabatini DM.
Saxton RA, et al.
Science. 2016 Jan 1;351(6268):53-8. doi: 10.1126/science.aad2087. Epub 2015 Nov 19.
Science. 2016.
PMID: 26586190
Free PMC article.
Item in Clipboard
Janus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domains.
Kim H, An S, Ro SH, Teixeira F, Park GJ, Kim C, Cho CS, Kim JS, Jakob U, Lee JH, Cho US.
Kim H, et al.
Nat Commun. 2015 Nov 27;6:10025. doi: 10.1038/ncomms10025.
Nat Commun. 2015.
PMID: 26612684
Free PMC article.
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