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A GABP-binding element in the Robo4 promoter is necessary for endothelial expression in vivo.
Blood. 2008 Sep 15;112(6):2336-9. doi: 10.1182/blood-2008-01-135079. Epub 2008 Jun 2.
Blood. 2008.
PMID: 18519813
Free PMC article.
Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama YS, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K, Li DY.
Jones CA, et al.
Nat Med. 2008 Apr;14(4):448-53. doi: 10.1038/nm1742. Epub 2008 Mar 16.
Nat Med. 2008.
PMID: 18345009
Free PMC article.
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The Robo4-TRAF7 complex suppresses endothelial hyperpermeability in inflammation.
Shirakura K, Ishiba R, Kashio T, Funatsu R, Tanaka T, Fukada SI, Ishimoto K, Hino N, Kondoh M, Ago Y, Fujio Y, Yano K, Doi T, Aird WC, Okada Y.
Shirakura K, et al.
J Cell Sci. 2019 Jan 2;132(1):jcs220228. doi: 10.1242/jcs.220228.
J Cell Sci. 2019.
PMID: 30510113
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A three-kilobase fragment of the human Robo4 promoter directs cell type-specific expression in endothelium.
Okada Y, Yano K, Jin E, Funahashi N, Kitayama M, Doi T, Spokes K, Beeler DL, Shih SC, Okada H, Danilov TA, Maynard E, Minami T, Oettgen P, Aird WC.
Okada Y, et al.
Circ Res. 2007 Jun 22;100(12):1712-22. doi: 10.1161/01.RES.0000269779.10644.dc. Epub 2007 May 10.
Circ Res. 2007.
PMID: 17495228
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Robo4 regulates the radial migration of newborn neurons in developing neocortex.
Zheng W, Geng AQ, Li PF, Wang Y, Yuan XB.
Zheng W, et al.
Cereb Cortex. 2012 Nov;22(11):2587-601. doi: 10.1093/cercor/bhr330. Epub 2011 Nov 28.
Cereb Cortex. 2012.
PMID: 22123939
Free PMC article.
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A mouse knockout library for secreted and transmembrane proteins.
Tang T, Li L, Tang J, Li Y, Lin WY, Martin F, Grant D, Solloway M, Parker L, Ye W, Forrest W, Ghilardi N, Oravecz T, Platt KA, Rice DS, Hansen GM, Abuin A, Eberhart DE, Godowski P, Holt KH, Peterson A, Zambrowicz BP, de Sauvage FJ.
Tang T, et al.
Nat Biotechnol. 2010 Jul;28(7):749-55. doi: 10.1038/nbt.1644. Epub 2010 Jun 20.
Nat Biotechnol. 2010.
PMID: 20562862
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