Expression of the Ha-ras suppressor family member 5 gene in the maturing rat testis

Biosci Biotechnol Biochem. 2008 May;72(5):1360-3. doi: 10.1271/bbb.70673. Epub 2008 May 7.

Abstract

We analyzed the gene expression of Ha-ras suppressor family member 5 (Hrasls5), which is considered to modulate the Ha-ras signaling cascade, from maturing rat testis. Expression was detected primarily in the spermatocytes in the maturing rat testis. The Hrasls5 gene product might function as a tumor suppressor as well as in spermatogenesis, as deduced from its amino acid sequence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Gene Expression Regulation, Developmental*
  • Male
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism
  • Rats
  • Rats, Sprague-Dawley
  • Spermatocytes / cytology
  • Spermatocytes / metabolism
  • Spermatogenesis
  • Testis / cytology
  • Testis / growth & development*
  • Testis / metabolism*
  • Tumor Suppressor Proteins / genetics*
  • Tumor Suppressor Proteins / metabolism

Substances

  • Plaat5 protein, rat
  • RNA, Messenger
  • Tumor Suppressor Proteins