Abstract
We analyzed the gene expression of Ha-ras suppressor family member 5 (Hrasls5), which is considered to modulate the Ha-ras signaling cascade, from maturing rat testis. Expression was detected primarily in the spermatocytes in the maturing rat testis. The Hrasls5 gene product might function as a tumor suppressor as well as in spermatogenesis, as deduced from its amino acid sequence.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Gene Expression Regulation, Developmental*
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Male
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RNA, Messenger / genetics
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RNA, Messenger / metabolism
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Rats
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Rats, Sprague-Dawley
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Spermatocytes / cytology
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Spermatocytes / metabolism
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Spermatogenesis
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Testis / cytology
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Testis / growth & development*
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Testis / metabolism*
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Tumor Suppressor Proteins / genetics*
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Tumor Suppressor Proteins / metabolism
Substances
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Plaat5 protein, rat
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RNA, Messenger
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Tumor Suppressor Proteins