Refinement of the localization of human butyrylcholinesterase to chromosome 3q26.1-q26.2 using a PCR-derived probe

Genomics. 1991 Oct;11(2):455-8. doi: 10.1016/0888-7543(91)90155-8.

Abstract

The gene for butyrylcholinesterase (EC 3.1.1.8) has been previously localized to three sites in the human genome, at 3q21, 3q26, and 16q21. In situ hybridization using a PCR-derived probe including the active site region gives a single hybridization signal and refines the localization to 3q26.1-q26.2.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Autoradiography
  • Butyrylcholinesterase / genetics*
  • Chromosome Mapping
  • Chromosomes, Human, Pair 3*
  • DNA Probes
  • Humans
  • Leukocytes
  • Nucleic Acid Hybridization
  • Polymerase Chain Reaction

Substances

  • DNA Probes
  • Butyrylcholinesterase