[R1 resection in the surgery of upper gastrointestinal tumors: relevance and therapeutic consequences]

F Lordick; K Ott; A Novotny; C Schuhmacher; J R Siewert

doi:10.1007/s00104-007-1381-x

[R1 resection in the surgery of upper gastrointestinal tumors: relevance and therapeutic consequences]

Chirurg. 2007 Sep;78(9):792-801. doi: 10.1007/s00104-007-1381-x.

[Article in German]

Authors

F Lordick¹, K Ott, A Novotny, C Schuhmacher, J R Siewert

Affiliation

¹ Nationales Centrum für Tumorerkrankungen (NCT), Universitätsklinikum, Im Neuenheimer Feld 350, 69120 Heidelberg, Germany. florian.lordick@med.uni-heidelberg.de

PMID: 17676284
DOI: 10.1007/s00104-007-1381-x

Abstract

Microscopically involved tumor margins are an important problem in the surgery of locally advanced esophageal and gastric carcinomas. We conducted a systematic review of the literature and a specific analysis of our own patient database. This article summarizes current knowledge of the incidence and prognosis of R1 resections in upper gastrointestinal cancers. Preoperative strategies for reducing the rate of R1 resections are presented, and the surgical options in case of R1 resection are discussed.

Publication types

Comparative Study
Review
Systematic Review

MeSH terms

Adenocarcinoma / diagnostic imaging
Adenocarcinoma / mortality
Adenocarcinoma / pathology
Adenocarcinoma / surgery*
Endosonography
Esophageal Neoplasms / diagnostic imaging
Esophageal Neoplasms / mortality
Esophageal Neoplasms / pathology
Esophageal Neoplasms / surgery*
Esophagus / pathology
Gastrectomy
Humans
Kaplan-Meier Estimate
Multicenter Studies as Topic
Neoadjuvant Therapy
Neoplasm Staging
Neoplasm, Residual / diagnosis
Neoplasm, Residual / diagnostic imaging
Neoplasm, Residual / pathology
Neoplasm, Residual / surgery*
Prognosis
Stomach / pathology
Stomach Neoplasms / diagnostic imaging
Stomach Neoplasms / mortality
Stomach Neoplasms / pathology
Stomach Neoplasms / surgery*
Time Factors