Analysis of JAK3, JAK2, and C-MPL mutations in transient myeloproliferative disorder and myeloid leukemia of Down syndrome blasts in children with Down syndrome

Blood. 2007 Aug 1;110(3):1077-9. doi: 10.1182/blood-2007-03-080374.
No abstract available

Publication types

  • Letter

MeSH terms

  • Child
  • Child, Preschool
  • Down Syndrome / complications
  • Down Syndrome / genetics*
  • Epigenesis, Genetic
  • Female
  • Genetic Predisposition to Disease
  • Humans
  • Janus Kinase 2 / genetics*
  • Janus Kinase 3 / genetics*
  • Leukemia, Myeloid / etiology
  • Leukemia, Myeloid / genetics*
  • Male
  • Mutation*
  • Myeloproliferative Disorders / etiology
  • Myeloproliferative Disorders / genetics*
  • Receptors, Thrombopoietin / genetics*

Substances

  • Receptors, Thrombopoietin
  • MPL protein, human
  • JAK2 protein, human
  • JAK3 protein, human
  • Janus Kinase 2
  • Janus Kinase 3