N2-benzyloxycarbonylguan-9-yl acetic acid derivatives as HIV-1 reverse transcriptase non-nucleoside inhibitors with decreased loss of potency against common drug-resistance mutations

ChemMedChem. 2007 Oct;2(10):1405-9. doi: 10.1002/cmdc.200700045.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetates / chemistry
  • Acetates / pharmacology*
  • Drug Resistance, Viral / genetics*
  • Guanine / analogs & derivatives*
  • Guanine / chemistry
  • Guanine / pharmacology
  • HIV Reverse Transcriptase / antagonists & inhibitors*
  • HIV-1 / drug effects*
  • HIV-1 / genetics
  • Kinetics
  • Reverse Transcriptase Inhibitors / chemistry
  • Reverse Transcriptase Inhibitors / pharmacology*

Substances

  • Acetates
  • Reverse Transcriptase Inhibitors
  • Guanine
  • reverse transcriptase, Human immunodeficiency virus 1
  • HIV Reverse Transcriptase