Abstract
Concordant expression of human hexokinase-1 and inorganic pyrophosphatase was established in somatic cell hybrids between thymidine kinase-deficient Chinese hamster cells and human fibroblasts carrying a translocation of the distal third of the long arm of chromosome 10 to chromosome 17. Neither human hexokinase-1 nor human inorganic pyrophosphatase expression segregated concordantly with human cytoplasmic glutamic-oxaloacetic transaminase expression.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Animals
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Aspartate Aminotransferases / genetics
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Cells, Cultured
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Chromosome Mapping*
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Chromosome Segregation
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Chromosomes, Human, Pair 10*
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Chromosomes, Human, Pair 17
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Cricetinae
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Cricetulus
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Hexokinase / genetics*
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Humans
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Hybrid Cells
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Inorganic Pyrophosphatase / genetics*
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Translocation, Genetic*
Substances
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Aspartate Aminotransferases
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HK1 protein, human
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Hexokinase
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Inorganic Pyrophosphatase