Localization of the structural genes for hexokinase-1 and inorganic pyrophosphatase on region (pter-->q24) of human chromosome 10

Cytogenet Cell Genet. 1976;17(6):338-42. doi: 10.1159/000130736.

Abstract

Concordant expression of human hexokinase-1 and inorganic pyrophosphatase was established in somatic cell hybrids between thymidine kinase-deficient Chinese hamster cells and human fibroblasts carrying a translocation of the distal third of the long arm of chromosome 10 to chromosome 17. Neither human hexokinase-1 nor human inorganic pyrophosphatase expression segregated concordantly with human cytoplasmic glutamic-oxaloacetic transaminase expression.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Aspartate Aminotransferases / genetics
  • Cells, Cultured
  • Chromosome Mapping*
  • Chromosome Segregation
  • Chromosomes, Human, Pair 10*
  • Chromosomes, Human, Pair 17
  • Cricetinae
  • Cricetulus
  • Hexokinase / genetics*
  • Humans
  • Hybrid Cells
  • Inorganic Pyrophosphatase / genetics*
  • Translocation, Genetic*

Substances

  • Aspartate Aminotransferases
  • HK1 protein, human
  • Hexokinase
  • Inorganic Pyrophosphatase