Evolving a thermostable DNA polymerase that amplifies from highly damaged templates

Angew Chem Int Ed Engl. 2007;46(17):3115-7. doi: 10.1002/anie.200603987.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / biosynthesis*
  • DNA / chemistry*
  • DNA / genetics
  • DNA / metabolism
  • DNA Damage*
  • DNA Replication*
  • DNA-Directed DNA Polymerase / genetics
  • DNA-Directed DNA Polymerase / metabolism*
  • Directed Molecular Evolution*
  • Enzyme Stability
  • Gene Amplification*
  • Molecular Structure
  • Temperature
  • Templates, Genetic
  • Thermodynamics

Substances

  • DNA
  • DNA-Directed DNA Polymerase