Promoter hypermethylation silences expression of the HoxA4 gene and correlates with IgVh mutational status in CLL

Leukemia. 2006 Jul;20(7):1326-9. doi: 10.1038/sj.leu.2404254. Epub 2006 May 11.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA Methylation*
  • Gene Expression Regulation, Leukemic*
  • Gene Silencing
  • Homeodomain Proteins / genetics*
  • Homeodomain Proteins / metabolism
  • Humans
  • Immunoglobulin Variable Region / genetics*
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
  • Mutation
  • Promoter Regions, Genetic / physiology
  • Transcription Factors

Substances

  • Homeodomain Proteins
  • Immunoglobulin Variable Region
  • Transcription Factors
  • HOXA4 protein, human