Abstract
A 50 year old patient with non-diagnosed HIV-infection at onset of his illness developed impairment of vision and temporary double vision combined with severe hemianopsia. With normal fundus and suspicious Herpes simplex iritis therapy with Acyclovir was started. Primarily the patient showed a good response to the therapy and loss of vision could be prevented. After 4 weeks CMV-retinitis developed. In spite of Gancyclovir therapy manifestation of total loss of vision after 6 weeks. Autopsy demonstrated signs of simultaneous a CMV-infection of the retina and a herpes simplex-infection of the optic nerve combined with a Non-Hodgkin-Lymphoma of the optic tract.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Acquired Immunodeficiency Syndrome / complications*
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Acquired Immunodeficiency Syndrome / diagnosis
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Acquired Immunodeficiency Syndrome / pathology
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Blindness / diagnosis
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Blindness / etiology*
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Blindness / pathology
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Brain / pathology
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Brain Neoplasms / complications*
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Brain Neoplasms / diagnosis
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Brain Neoplasms / pathology
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Choroid / pathology
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Cytomegalovirus Infections / complications*
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Cytomegalovirus Infections / diagnosis
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Cytomegalovirus Infections / pathology
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Humans
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Keratitis, Dendritic / complications*
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Keratitis, Dendritic / diagnosis
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Keratitis, Dendritic / pathology
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Lymphoma, Non-Hodgkin / complications*
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Lymphoma, Non-Hodgkin / diagnosis
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Lymphoma, Non-Hodgkin / pathology
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Male
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Middle Aged
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Opportunistic Infections / complications*
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Opportunistic Infections / diagnosis
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Opportunistic Infections / pathology
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Optic Nerve / pathology
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Pigment Epithelium of Eye / pathology
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Retina / pathology
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Retinal Detachment / diagnosis
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Retinal Detachment / etiology
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Retinal Detachment / pathology
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Retinitis / complications*
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Retinitis / diagnosis
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Retinitis / pathology
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Visual Fields / physiology