ABO, Rh, MNS, Duffy, Kidd,Yt, Scianna, and Colton blood group systems in indigenous Chinese

Immunohematology. 2005;21(1):10-4.

Abstract

The frequencies of selected alleles in the ABO, Rh, MNS, Duffy, Kidd, Yt, Scianna, and Colton blood group systems were determined among four indigenous Chinese ethnic populations: Han, Tajik, She, and Yugu. Genotypes were determined by PCR or PCR with sequence specific primers (PCR-SSP). In the Han population, the frequencies of A1, A2, B, and O1 alleles were 0.189, 0.003, 0.170, and 0.638, respectively, and the O2 allele was not identified. Among D+ Hans, the frequencies of C and c alleles were 0.67 and 0.33 and the frequencies of E and e were 0.22 and 0.78, respectively. Among D- Hans, the frequencies of C and c alleles were 0.23 and 0.77 and the frequencies of E and e were 0.04 and 0.96, respectively. The frequencies of M and N alleles were 0.478 and 0.522 among Hans and 0.655 and 0.345 among Tajiks, respectively. The frequencies of Fya and Fyb alleles were 0.94 and 0.06 among Hans and 0.98 and 0.02 among Shes, respectively. The frequencies of Jka and Jkb alleles were 0.49 and 0.51 among Hans and 0.56 and 0.44 among Shes, respectively. The frequency of the Yta allele was 1.00 among Hans. The frequencies of Yta and Ytb alleles were 0.94 and 0.06 among Tajiks, respectively. The frequency of the Sc1 allele was 1.00 in both Han and Tajik ethnic populations. The frequency of the Coa allele was 1.00 in Han, She, and Tajik ethnic populations.

MeSH terms

  • ABO Blood-Group System / genetics
  • Antigens, Surface / genetics
  • Aquaporin 1
  • Aquaporins / genetics
  • Autoantigens
  • Blood Group Antigens / genetics*
  • Blood Grouping and Crossmatching / statistics & numerical data*
  • Butyrophilins
  • China / ethnology
  • Duffy Blood-Group System / genetics
  • Gene Frequency
  • Genetic Variation
  • Genotype
  • Humans
  • Kidd Blood-Group System / genetics
  • MNSs Blood-Group System / genetics
  • Polymerase Chain Reaction
  • Rh-Hr Blood-Group System / genetics
  • Ribonucleoproteins, Small Nuclear / genetics
  • snRNP Core Proteins

Substances

  • ABO Blood-Group System
  • AQP1 protein, human
  • Antigens, Surface
  • Aquaporins
  • Autoantigens
  • Blood Group Antigens
  • Butyrophilins
  • Duffy Blood-Group System
  • Kidd Blood-Group System
  • MNSs Blood-Group System
  • Rh-Hr Blood-Group System
  • Ribonucleoproteins, Small Nuclear
  • scianna antigens
  • snRNP Core Proteins
  • Aquaporin 1