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Munc13-4 is an effector of rab27a and controls secretion of lysosomes in hematopoietic cells.
Mol Biol Cell. 2005 Feb;16(2):731-41. doi: 10.1091/mbc.e04-10-0923. Epub 2004 Nov 17.
Mol Biol Cell. 2005.
PMID: 15548590
Free PMC article.
Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A.
Zur Stadt U, Beutel K, Kolberg S, Schneppenheim R, Kabisch H, Janka G, Hennies HC.
Zur Stadt U, et al.
Hum Mutat. 2006 Jan;27(1):62-8. doi: 10.1002/humu.20274.
Hum Mutat. 2006.
PMID: 16278825
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Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding.
Cetica V, Hackmann Y, Grieve S, Sieni E, Ciambotti B, Coniglio ML, Pende D, Gilmour K, Romagnoli P, Griffiths GM, Aricò M.
Cetica V, et al.
J Allergy Clin Immunol. 2015 May;135(5):1310-8.e1. doi: 10.1016/j.jaci.2014.08.039. Epub 2014 Oct 11.
J Allergy Clin Immunol. 2015.
PMID: 25312756
Free PMC article.
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Extracellular Fibrinogen-binding Protein (Efb) from Staphylococcus aureus Inhibits the Formation of Platelet-Leukocyte Complexes.
Posner MG, Upadhyay A, Abubaker AA, Fortunato TM, Vara D, Canobbio I, Bagby S, Pula G.
Posner MG, et al.
J Biol Chem. 2016 Feb 5;291(6):2764-76. doi: 10.1074/jbc.M115.678359. Epub 2015 Dec 1.
J Biol Chem. 2016.
PMID: 26627825
Free PMC article.
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RhoG deficiency abrogates cytotoxicity of human lymphocytes and causes hemophagocytic lymphohistiocytosis.
Kalinichenko A, Perinetti Casoni G, Dupré L, Trotta L, Huemer J, Galgano D, German Y, Haladik B, Pazmandi J, Thian M, Yüce Petronczki Ö, Chiang SC, Taskinen M, Hekkala A, Kauppila S, Lindgren O, Tapiainen T, Kraakman MJ, Vettenranta K, Lomakin AJ, Saarela J, Seppänen MRJ, Bryceson YT, Boztug K.
Kalinichenko A, et al.
Blood. 2021 Apr 15;137(15):2033-2045. doi: 10.1182/blood.2020008738.
Blood. 2021.
PMID: 33513601
Free PMC article.
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